伪装成Vogt-小柳-原田综合征的血管内淋巴瘤。
Intravascular lymphoma masquerading as Vogt-Koyanagi-Harada syndrome.
作者信息
Pahk Patricia J, Todd Derrick J, Blaha Gregory R, Soukiasian Sarkis H, Landmann Dan S, Craven Donald E, Tronic Bruce S, Zabar Yuval, Marx Jeffrey L
机构信息
Department of Ophthalmology, Lahey Clinic, Burlington, Massachusetts 01805, USA.
出版信息
Ocul Immunol Inflamm. 2008 May-Jun;16(3):123-6. doi: 10.1080/09273940802023810.
PURPOSE
To describe the clinical course of a case of intravascular lymphoma.
DESIGN
Case report.
METHODS
Retrospective chart review.
RESULTS
A 56-year-old man presented with blurry vision associated with fever and decreased hearing. Ocular exam including fluorescein angiography and OCT was consistent with Vogt-Koyanagi-Harada syndrome and the patient initially improved with corticosteroids. Clinical deterioration led to further systemic workup and revealed intravascular lymphoma. The patient was started on chemotherapy with resolution of visual complaints.
CONCLUSIONS
Intravascular lymphoma can present as a masquerade of VKH syndrome. Diagnosis can be aided with measurement of LDH and skin biopsy.
目的
描述1例血管内淋巴瘤患者的临床病程。
设计
病例报告。
方法
回顾性病历审查。
结果
一名56岁男性出现与发热和听力下降相关的视力模糊。包括荧光素血管造影和光学相干断层扫描在内的眼部检查结果符合Vogt-小柳原田综合征，患者最初使用皮质类固醇治疗后病情有所改善。临床病情恶化促使进一步进行全身检查，结果显示为血管内淋巴瘤。患者开始接受化疗，视觉症状得以缓解。
结论
血管内淋巴瘤可表现为伪装成VKH综合征。测定乳酸脱氢酶和皮肤活检有助于诊断。
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