Gun Feryal, Toker Alper, Kaya Serkan, Tanju Serhan, Dilege Sukru, Celik Alaettin, Salman Tansu, Yilmazbayhan Dilek
Department of Pediatric Surgery, Istanbul University, Istanbul Medical School, Instanbul, Turkey.
Pediatr Hematol Oncol. 2008 Jun;25(5):393-7. doi: 10.1080/08880010802104593.
A cytological diagnosis is essential for a definitive diagnosis in children who have paratracheal lesions. Thirteen pediatric patients were biopsied using cervical mediastinoscopy. Age, gender, preoperative diagnosis, and postoperative biopsy results and complications were reviewed. Five patients had mediastinal lesions residuing or recurring after chemotherapy for either Hodgkin disease or non-Hodgkin lymphoma. In 2 of these patients, the diagnosis was recurrent disease. Among the 8 patients presenting with a paratracheal mass or enlarged lymph nodes, histopathologic diagnosis showed tuberculosis in 3 children, Hodgkin disease in 2 children, and histiocytosis X and non-Hodgkin lymphoma 1 patient in each. This study shows that cervical mediastinoscopy gave 100% correct diagnosis for mediastinal residual malignancies or uncommon forms of mycobacterium tuberculosis with paratracheal masses.
对于患有气管旁病变的儿童,细胞学诊断对于明确诊断至关重要。13例儿科患者接受了颈部纵隔镜活检。回顾了年龄、性别、术前诊断、术后活检结果及并发症。5例患者在接受霍奇金病或非霍奇金淋巴瘤化疗后出现纵隔病变残留或复发。其中2例患者诊断为疾病复发。在8例出现气管旁肿块或淋巴结肿大的患者中,组织病理学诊断显示3例儿童为结核病,2例儿童为霍奇金病,组织细胞增多症X和非霍奇金淋巴瘤各1例。本研究表明,颈部纵隔镜检查对于纵隔残留恶性肿瘤或伴有气管旁肿块的罕见结核分枝杆菌形式给出了100%的正确诊断。