Schaison G, Weil M, Backes C, Jacquillat C L, Bussel A, Perol Y
Sem Hop. 1976 Jan 9;52(2):99-103.
During acute lymphoblastic leukemia in children, bacterial infections occur during initial treatment, whereas virus infections are observed during remission. Mycoses and pneumocystis carinii infections are the commonest late complications. During agranulocytosis, any prolonged fever should be considered as due to infection and probably septicemia. The bacteria are usually of digestive origin. Antibiotic therapy is only very inconstantly efficacious, and the course follows closely the number of granular cells, thus justifying the use of white cell transfusions.
在儿童急性淋巴细胞白血病期间，细菌感染发生在初始治疗阶段，而病毒感染则在缓解期出现。真菌病和卡氏肺孢子虫感染是最常见的晚期并发症。在粒细胞缺乏症期间，任何持续发热都应被视为由感染引起，可能是败血症。细菌通常来源于消化道。抗生素治疗效果极不稳定，病程与粒细胞数量密切相关，因此白细胞输血有其合理性。
