Schlebusch H, Liappis N, Sorger M, Paffenholz I, Koch H C
Zentrum für Geburtshilfe und Frauenheilkunde, Universität Bonn.
Klin Padiatr. 1991 May-Jun;203(3):173-7. doi: 10.1055/s-2007-1025425.
The determination of fructosamine in serum of healthy newborns, children and adolescents by a new colorimetric method leads to an age-dependent reference range. Correction of the values for total protein yields a median of the results, which is not dependent on age and the upper limit of the reference range is not significantly different from that of healthy adults; this does not hold true for referral to albumin. As the half-life time of glycated serum proteins is shorter (mean 20 days) than that of hemoglobin A1c, fructosamine can provide useful additional informations about the diabetic control of children and adolescents (medium-term record of blood glucose).
采用一种新的比色法测定健康新生儿、儿童及青少年血清中的果糖胺,得出了一个与年龄相关的参考范围。对总蛋白值进行校正后得出结果的中位数,该中位数不依赖于年龄,且参考范围的上限与健康成年人的上限无显著差异;但以白蛋白为参照时情况并非如此。由于糖化血清蛋白的半衰期(平均20天)比血红蛋白A1c的半衰期短,果糖胺可为儿童及青少年的糖尿病控制情况(血糖的中期记录)提供有用的补充信息。