Lê Quang C, Delèvaux I, Trouillier S, André M, Souweine B, Tridon A, Cordier J-F, Aumaître O
Service de médecine interne, hôpital G.-Montpied, CHU de Clermont-Ferrand, 58, rue Montalembert, 63003 Clermont-Ferrand cedex 1, France.
Rev Med Interne. 2008 Dec;29(12):1038-42. doi: 10.1016/j.revmed.2008.03.001. Epub 2008 Jun 24.
Isolated pulmonary involvement in Goodpasture's syndrome is exceptionally described. We report a 36-year-old woman with pulmonary haemorrhage and review 28 additional cases of the literature. In fact, these patients had often mild urine abnormalities and constant glomerular lesions. Antiglomerular basement membrane antibodies testing should be systematically ordered in patients presenting with alveolar haemorrhage. Goodpasture's syndrome without renal abnormality could be an early stage of the disease with a better prognosis.
孤立性肺部受累在肺出血肾炎综合征中鲜有描述。我们报告了一名36岁有肺出血的女性，并复习了文献中的另外28例病例。事实上，这些患者常有轻度尿液异常和持续性肾小球病变。对于出现肺泡出血的患者，应系统性地进行抗肾小球基底膜抗体检测。无肾脏异常的肺出血肾炎综合征可能是疾病的早期阶段，预后较好。
