基于通用三羟甲基氨基甲烷（TRIS）和甘露糖苷衍生物的糖树枝状聚合物支架的快速合成。
Expeditive synthesis of glycodendrimer scaffolds based on versatile TRIS and mannoside derivatives.
作者信息
Chabre Yoann M, Contino-Pépin Christiane, Placide Virginie, Shiao Tze Chieh, Roy René
机构信息
Department of Chemistry, Université du Québec à Montréal, P.O. Box 8888, Succ. Centre-Ville Montréal, Québec, Canada H3C 3P8.
出版信息
J Org Chem. 2008 Jul 18;73(14):5602-5. doi: 10.1021/jo8008935. Epub 2008 Jun 24.
PMID:18572921
Abstract
A new family of glycodendrimer scaffolds containing 12 and 18 peripheral alpha-d-mannopyranosidic units has been synthesized by Cu(I)-catalyzed [1,3]-dipolar cycloadditions using sulfurated dendritic scaffolds bearing alkyne functionalities and novel TRIS derivatives.
摘要
通过使用带有炔基官能团的硫化树枝状支架和新型三（羟甲基）氨基甲烷衍生物，通过铜（I）催化的[1,3] -偶极环加成反应，合成了一个新的包含12个和18个外围α-D-甘露吡喃糖苷单元的糖树枝状支架家族。
Zotero 插件