Bröder Arndt, Herwig Andrea, Teipel Stefan, Fast Kristina
Department of Psychology, University of Bonn, Bonn, Germany.
Psychol Aging. 2008 Jun;23(2):353-65. doi: 10.1037/0882-7974.23.2.353.
The authors compared patients with mild cognitive impairment with healthy older adults and young control participants in a free recall test in order to locate potential qualitative differences in normal and pathological memory decline. Analysis with an extended multitrial version of W. H. Batchelder and D. M. Riefer's (1980) pair-clustering model revealed globally decelerated learning and an additional retrieval deficit in patients with mild cognitive impairment but not in healthy older adults. Results thus suggest differences in memory decline between normal and pathological aging that may be useful for the detection of risk groups for dementia, and they illustrate the value of model-based disentangling of processes and of multitrial tests for early detection of dementia.
作者在一项自由回忆测试中,将轻度认知障碍患者与健康老年人及年轻对照参与者进行比较,以便找出正常和病理性记忆衰退中潜在的质性差异。运用W.H. 巴奇尔德和D.M. 里弗(1980年)的配对聚类模型的扩展多试验版本进行分析发现,轻度认知障碍患者的学习整体减速,且存在额外的检索缺陷,而健康老年人则没有。因此,研究结果表明正常衰老和病理性衰老在记忆衰退方面存在差异,这可能有助于检测痴呆风险群体,并且说明了基于模型的过程分解和多试验测试对早期检测痴呆的价值。