Jin Ruyun, Grunkemeier Gary L, Brown Jeremiah R, Furnary Anthony P
Medical Data Research Center, Providence Health & Services, Portland, OR 97225, USA.
Ann Thorac Surg. 2008 Jul;86(1):1-3. doi: 10.1016/j.athoracsur.2008.05.007.
Glomerular filtration rate (GFR) is an important clinical indicator of kidney function. It can be used as an independent predictor of long-term survival after cardiac surgery. Definition, methods of measurement, and corrected value by body surface area are briefly introduced in this paper. Details of the calculation of estimated GFR (eGFR) by Levey's formula with serum creatinine, age, gender, and race are offered. The relationship between estimated GFR and the four factors is shown graphically and discussed. An eGFR/creatinine conversion table for individual patients derived from the eGFR equation with clinically significant cutpoints is given, which can be used by physicians as a pragmatic reference.
肾小球滤过率(GFR)是肾功能的一项重要临床指标。它可用作心脏手术后长期生存的独立预测指标。本文简要介绍了其定义、测量方法以及经体表面积校正的值。文中提供了利用血清肌酐、年龄、性别和种族,通过Levey公式计算估算肾小球滤过率(eGFR)的详细方法。以图表形式展示并讨论了估算肾小球滤过率与这四个因素之间的关系。给出了根据eGFR方程得出的、具有临床意义切点的个体患者eGFR/肌酐换算表,可供医生作为实用参考。