Lebedeva S A, Grebtsova N N, Cherniavskaia A S, Kuznetsova L S, Vasil'eva E A
Mol Gen Mikrobiol Virusol. 1991 Mar(3):5-10.
On the model of Yersinia transconjugants (Yersinia pestis, Yersinia pseudotuberculosis, Yersinia enterocolitica) carrying the conjugative cointegrates containing the 47 and 65 Md plasmids from Yersinia pestis the data were obtained on the different affects of the latter plasmids on the lethality and immunogenicity conferred by the host bacterial cells. The plasmid effects were drastically different during bacterial infection in mice or guinea pigs. The possibility of appearance of the recombinant Yersinia in natural epizootic foci of plague and suggestions on their regulating role are discussed.
以携带来自鼠疫耶尔森菌的47 Md和65 Md质粒的接合共整合体的耶尔森菌转接合子(鼠疫耶尔森菌、假结核耶尔森菌、小肠结肠炎耶尔森菌)为模型,获得了关于后两种质粒对宿主细菌细胞赋予的致死性和免疫原性的不同影响的数据。在小鼠或豚鼠的细菌感染过程中,质粒的影响差异很大。讨论了重组耶尔森菌在鼠疫自然疫源地出现的可能性及其调节作用。