O'Brien Sean M, Delong Elizabeth R, Peterson Eric D
Duke Clinical Research Institute, Box 17969, Durham, NC 27715, USA.
Arch Intern Med. 2008 Jun 23;168(12):1277-84. doi: 10.1001/archinte.168.12.1277.
Process performance measures are increasingly used to assess and reward hospital quality. The impact of small hospital case volumes on such measures is not clear.
Using data from the Hospital Quality Alliance, we examined hospital performance for 8 publicly reported process measures for acute myocardial infarction (AMI) from 3761 US hospitals during the reporting period of January to December 2005. For each performance measure, we examined the association between hospital case volume, process performance, and designation as a "top hospital" (performance at or above the 90% percentile score).
Sample sizes available for process performance assessment varied considerably, ranging from a median of 3 patients per hospital for timely administration of thrombolytics therapy to 62 patients for aspirin given on arrival at the hospital. In aggregate, hospitals with larger AMI case volumes had better process performance; for example, use of beta-blockers at arrival rose from 72% of patients at hospitals with less than 10 AMI cases to 80% of patients at hospitals with more than 100 cases (P < .001 for volume trend). In contrast, owing to an artifact of wide sampling variation in sites with small denominators, classification of a center as a top hospital actually declined rapidly with increasing case volume using current analytic methods (P < .001). This unexpected association persisted after excluding very low volume centers (<25 cases) and when using Achievable Benchmarks of Care. Using hierarchical models removed the paradoxical association but may have introduced a bias in the opposite direction.
Large-volume hospitals had better aggregate performance but were less likely to be identified as top hospitals. Methods that account for small and unequal denominators are needed when assessing hospital process measure performance.
过程绩效指标越来越多地用于评估和奖励医院质量。小型医院病例数对此类指标的影响尚不清楚。
利用医院质量联盟的数据,我们考察了2005年1月至12月报告期内美国3761家医院8项公开报告的急性心肌梗死(AMI)过程指标的医院绩效。对于每项绩效指标,我们考察了医院病例数、过程绩效与被指定为“顶级医院”(绩效处于或高于第90百分位数得分)之间的关联。
可用于过程绩效评估的样本量差异很大,从每家医院及时进行溶栓治疗的中位数3例患者到入院时给予阿司匹林的62例患者不等。总体而言,AMI病例数较多的医院过程绩效更好;例如,入院时使用β受体阻滞剂的患者比例从AMI病例数少于10例的医院的72%升至病例数超过100例的医院的80%(病例数趋势P<.001)。相比之下,由于分母较小的部位抽样差异较大这一假象,按照当前分析方法,随着病例数增加,将一个中心归类为顶级医院的比例实际上迅速下降(P<.001)。在排除病例数极少的中心(<25例)后以及使用可实现的护理基准时,这种意外关联仍然存在。使用分层模型消除了这种矛盾关联,但可能在相反方向引入了偏差。
病例数多的医院总体绩效更好,但被认定为顶级医院的可能性较小。评估医院过程指标绩效时需要采用考虑到分母小且不相等的方法。