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丹麦青少年和青年的个人及父母精神病史与自杀风险:一项基于人群的研究。

Individual and parental psychiatric history and risk for suicide among adolescents and young adults in Denmark: a population-based study.

作者信息

Stenager Kirstina, Qin Ping

机构信息

Faculty of Social Sciences, University of Aalborg, Aalborg, Denmark.

出版信息

Soc Psychiatry Psychiatr Epidemiol. 2008 Nov;43(11):920-6. doi: 10.1007/s00127-008-0385-2. Epub 2008 Jun 20.

Abstract

BACKGROUND

Both individual and familial histories of mental illness are substantial risk factors for suicide in young people.

AIM

To explore suicide risk among adolescents and young adults according to detailed aspects of individual and parental psychiatric admission history.

METHODS

A nested case-control study was undertaken using data from Danish population registers to include 4,142 suicide cases and 82,840 matched controls aged 9-35 years. Data were analyzed with conditional logistic regression.

RESULTS

A history of hospitalized psychiatric illness was a strong risk factor for suicide in adolescents and young adults, and the effect of such a history was greater in females than males. The elevated risk peaked in the two periods immediately after admission and discharge for both sexes, and exceeded in females who had multiple admissions and in males who were diagnosed with schizophrenia, affective disorders or substance abuse disorders. At the same time, a parental psychiatric history constituted a substantial risk factor for suicide in young people, in particular, if having a mother admitted for psychiatric illness. The elevated risk associated with parental psychiatric history was greater in females than in males, and tended to be more prominent during the first few years after admission of a parent.

CONCLUSION

Prevention strategies should aim at improving treatment and care to young people with psychiatric problems and at providing social support and psychological consultation to children with parental psychiatric illness.

摘要

背景

精神疾病的个人史和家族史都是年轻人自杀的重要风险因素。

目的

根据个人和父母精神科住院史的详细情况,探讨青少年和青年成人的自杀风险。

方法

采用丹麦人口登记数据进行巢式病例对照研究,纳入4142例自杀病例和82840例年龄在9至35岁的匹配对照。采用条件逻辑回归分析数据。

结果

精神科住院病史是青少年和青年成人自杀的一个强有力的风险因素,且该病史对女性的影响大于男性。这种风险升高在男女两性入院和出院后的两个时期达到峰值,在多次入院的女性以及被诊断患有精神分裂症、情感障碍或物质使用障碍的男性中风险更高。同时,父母的精神病史是年轻人自杀的一个重要风险因素,特别是如果母亲有精神科住院史。父母精神病史相关的风险升高对女性的影响大于男性,并且在父母入院后的头几年往往更为突出。

结论

预防策略应旨在改善对有精神问题的年轻人的治疗和护理,并为父母有精神疾病的儿童提供社会支持和心理咨询。

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