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急性和复发性病毒性脑膜炎。

Acute and recurrent viral meningitis.

机构信息

Larry E. Davis, MD New Mexico VA Health Care System, Neurology Service, 1501 San Pedro Drive SE, Albuquerque, NM 87108, USA.

出版信息

Curr Treat Options Neurol. 2008 May;10(3):168-77. doi: 10.1007/s11940-008-0018-9.

Abstract

Acute viral meningitis is the most common infection of the central nervous system. Most cases occur in children and young adults and are due to enteroviruses. Although the common causes of acute viral meningitis still lack treatment with an effective antiviral agent, management of patients is changing because of better and more rapid diagnostic tests to determine the exact viral etiology. These tests reduce the cost of workups and shorten hospitalizations. Recurrent meningitis is less common, with most cases caused by herpes simplex virus 2 in young adults. Early administration of antiviral drugs such as acyclovir, valaciclovir, or famciclovir can shorten the duration of an episode of aseptic meningitis. Daily prophylactic administration of any of these medicines also reduces the frequency of future episodes.

摘要

急性病毒性脑膜炎是中枢神经系统最常见的感染。大多数病例发生在儿童和青年,由肠道病毒引起。虽然急性病毒性脑膜炎的常见病因仍缺乏有效的抗病毒药物治疗,但由于更好、更快速的诊断检测来确定确切的病毒病因,患者的治疗方法正在发生变化。这些测试降低了检查费用并缩短了住院时间。复发性脑膜炎较为少见,大多数病例由单纯疱疹病毒 2 在青年中引起。早期给予抗病毒药物,如阿昔洛韦、伐昔洛韦或泛昔洛韦,可以缩短无菌性脑膜炎发作的时间。这些药物中的任何一种的每日预防性给药也可以减少未来发作的频率。

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