Sqalli Tarik Houssaini, Laboudi Asmaa, Arrayhani Mohamed, Benamar Loubna, Amar Yamama, Ouzeddoun Naima, Bayahia Rabea, Rhou Hakima
Nephrology Department, Ibn Sina University Hospital, Rabat, Morocco.
Saudi J Kidney Dis Transpl. 2008 Jul;19(4):551-3.
Urinary tract infection (UTI) remains the most common infectious complication in renal transplant recipients. We aimed in our study to describe the epidemiological patterns and evaluate the favouring factors of UTI in our renal allograft recipients. We evaluated retrospectively all the UTIs in 47 kidney recipients transplanted from living-related kidney donors in Rabat University Hospital, Morocco, from January 1998 to December 2005. The mean follow-up was 28+/-19 months. The mean age of the patients was 32+/-10 years with a male/female ratio of 1.35/1. Twenty patients (42%) suffered at least one UTI episode. UTIs were asymptomatic in 70% of the patients, while manifested as acute pyelonephritis in 17% and uncomplicated acute bacterial cystitis in 13%. UTI episodes occurred in 68% of the patients during the first 3 months post-kidney transplantation with a recurrence rate of 55%, and all the patients experienced a favourable course. Gram-negative bacilli were the principally isolated agents; E. Coli was found in 60% of the patients and Klebsiella in 30%. UTI was more common in females (p=0.04) and cases of post transplantation vesicoureteral reflux (p=0.03). The graft survival rate at the end of the study was comparable for both UTI and non-UTI groups.
尿路感染(UTI)仍然是肾移植受者中最常见的感染性并发症。我们开展本研究的目的是描述肾移植受者中UTI的流行病学模式,并评估其相关影响因素。我们回顾性评估了1998年1月至2005年12月在摩洛哥拉巴特大学医院接受亲属活体肾移植的47例肾移植受者发生的所有UTI情况。平均随访时间为28±19个月。患者的平均年龄为32±10岁,男女比例为1.35:1。20例患者(42%)至少发生过一次UTI发作。70%的患者UTI无症状,17%表现为急性肾盂肾炎,13%表现为单纯性急性细菌性膀胱炎。68%的患者在肾移植后的前3个月内发生UTI发作,复发率为55%,所有患者病情均呈良性转归。革兰氏阴性杆菌是主要的分离病原体;60%的患者分离出大肠杆菌,30%分离出克雷伯菌。UTI在女性中更为常见(p=0.04),在移植后膀胱输尿管反流患者中也更为常见(p=0.03)。研究结束时,UTI组和非UTI组的移植物存活率相当。