Lester Todd, Xu Haodong
Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY 14642, USA.
Appl Immunohistochem Mol Morphol. 2008 Oct;16(5):507-9. doi: 10.1097/PAI.0b013e31815e927e.
Malignant mesotheliomas occur in the pleura, peritoneum, pericardium, and tunica vaginalis. The majority of tumors are pleural in origin. The typical pattern of spread is usually contiguous or via implantation. Hematogenous or lymphatic metastasis is not uncommon; however, metastasis to bone has rarely been well documented. This is a case report of malignant pleural mesothelioma metastatic to the femur with a pathologic fracture of femoral neck.
恶性间皮瘤发生于胸膜、腹膜、心包膜和鞘膜。大多数肿瘤起源于胸膜。典型的扩散模式通常是连续性的或通过种植转移。血行转移或淋巴转移并不少见；然而，转移至骨的情况鲜有详尽记录。本文报告一例发生股骨转移并伴有股骨颈病理性骨折的恶性胸膜间皮瘤病例。
