Kramer Barry Alan, Kadar Andrew G, Clark Kerri
Department of Psychiatry and Behavioral Neurosciences, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
J ECT. 2008 Jun;24(2):152-5. doi: 10.1097/YCT.0b013e318158e96f.
To determine, in a nonblinded trial, if the Neuro-Wrap system is effective in reducing the severity of pain in patients with severe post-electroconvulsive therapy (ECT) headaches not adequately responsive to routine analgesic treatment.
A very troubling side effect of ECT is severe post-ECT headaches. Although these headaches usually respond to routine analgesic medication, some patients continue to experience severe headache despite treatment. This very unpleasant sensation, repeated with each ECT, may cause patients to prematurely stop ECT and experience a relapse in their psychiatric symptoms. "Cold therapy" has been used for a long time as an adjunct to treat headache and pain. The Neuro-Wrap system is a method to provide temperature-controlled cooling to the head without the need to frequently reapply ice packs or physically hold the ice packs in position. It has been used successfully for patients with migraine headaches. This is the first report of its use with patients experiencing severe post-ECT headaches.
The study comprised a total of 14 patients receiving ECT who experienced a severe headache for 2 successive ECT treatments or 2 of their last 4 treatments and who had only partial or no response to usual analgesic treatment for their headache. After completion of the ECT, the Neuro-Wrap was placed on the head of the patient for a maximum of 40 minutes. Patients continued to receive analgesic medication as needed for relief of headache pain. Patients were their own control group.
A total of 85 Neuro-Wrap treatments were given to 14 patients ranging in age from 23 to 71 years old. Nine patients reported clearly positive results on 67 different occasions. Three reported mild alleviation of headaches on 15 occasions. The remaining 2 patients had a total of 3 treatments with no benefit. After the initial treatment, 12 of 14 patients wanted to use the machine after all their subsequent ECT sessions.
Cold therapy with Neuro-Wrap is an effective alternative treatment for refractory headaches caused by ECT.
在一项非盲法试验中,确定Neuro-Wrap系统对于常规镇痛治疗反应欠佳的严重电休克治疗(ECT)后头痛患者减轻疼痛严重程度是否有效。
ECT一个非常令人困扰的副作用是严重的ECT后头痛。尽管这些头痛通常对常规镇痛药有反应,但一些患者尽管接受了治疗仍持续经历严重头痛。这种非常不愉快的感觉,每次ECT都会出现,可能导致患者过早停止ECT,并使精神症状复发。“冷疗法”长期以来一直用作治疗头痛和疼痛的辅助手段。Neuro-Wrap系统是一种无需频繁重新敷用冰袋或手动固定冰袋位置即可对头进行温度控制冷却的方法。它已成功用于偏头痛患者。这是其用于ECT后严重头痛患者的首次报告。
该研究共纳入14例接受ECT治疗的患者,这些患者在连续2次ECT治疗或最后4次治疗中的2次出现严重头痛,且对头痛的常规镇痛治疗仅有部分反应或无反应。ECT结束后,将Neuro-Wrap置于患者头部,最长40分钟。患者根据需要继续接受镇痛药以缓解头痛。患者自身作为对照组。
14例年龄在23至71岁之间的患者共接受了85次Neuro-Wrap治疗。9例患者在67个不同场合报告了明显的阳性结果。3例在15个场合报告头痛略有缓解。其余2例患者共接受3次治疗,无益处。首次治疗后,14例患者中有12例希望在所有后续ECT治疗后使用该设备。
Neuro-Wrap冷疗法是ECT所致难治性头痛的一种有效替代治疗方法。