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企业支架用于复杂颅内动脉瘤血管内治疗的初步经验:潜在优势和局限性特征

Preliminary experience with the enterprise stent for endovascular treatment of complex intracranial aneurysms: potential advantages and limiting characteristics.

作者信息

Lubicz Boris, François Olivier, Levivier Marc, Brotchi Jacques, Balériaux Danielle

机构信息

Department of Neuroradiology, Erasme University Hospital, Brussels, Belgium.

出版信息

Neurosurgery. 2008 May;62(5):1063-9; discussion 1069-70. doi: 10.1227/01.neu.0000325868.06764.de.

DOI:10.1227/01.neu.0000325868.06764.de
PMID:18580804
Abstract

OBJECTIVE

Stent-assisted coiling is an accepted endovascular treatment (EVT) for complex intracranial aneurysms. The Enterprise self-expandable stent (Cordis, Miami Lakes, FL) is a new retractable stent that is delivered via a conventional coiling catheter to potentially circumvent the limitations of other stents. The aim of this study was to evaluate the use of this stent for EVT of complex aneurysms.

METHODS

Between January and May 2007, 14 patients with 15 unruptured wide-necked or fusiform aneurysms were treated. EVT consisted of stent placement and subsequent endosaccular coiling. Clinical outcome was assessed with the modified Glasgow Outcome Scale.

RESULTS

EVT was successfully performed and led to an excellent outcome in all patients. The stent was easily navigated and precisely positioned in all cases. However, the stent's visibility was poor once it was delivered. Moreover, procedural complications occurred in three patients, including stent migration (n = 1) and coil protrusion between the stent and the vessel wall (n = 2). In these latter two cases, a remodeling balloon was required to assist in delivery of the coils. No clinical incidence of complications was observed when the parent artery had a diameter of more than 4 mm. Angiographic results consisted of eight complete occlusions, four neck remnants, and three incomplete occlusions.

CONCLUSION

The Enterprise stent is very useful for EVT of complex intracranial aneurysms because it is easy to navigate and place precisely. However, the currently available stent has two relatively limiting characteristics: 1) it has poor visibility, and 2) it should only be used for aneurysms located on a parent artery with a maximal diameter of 4 mm.

摘要

目的

支架辅助弹簧圈栓塞术是治疗复杂颅内动脉瘤公认的血管内治疗方法。Enterprise自膨式支架(美国科迪斯公司,迈阿密湖,佛罗里达州)是一种新型可回收支架,可通过传统的弹簧圈栓塞导管输送,有可能克服其他支架的局限性。本研究旨在评估该支架在复杂动脉瘤血管内治疗中的应用。

方法

2007年1月至5月,对14例患者的15个未破裂的宽颈或梭形动脉瘤进行了治疗。血管内治疗包括支架置入及随后的瘤内弹簧圈栓塞。采用改良格拉斯哥预后量表评估临床结局。

结果

血管内治疗均成功实施,所有患者预后良好。在所有病例中,支架均易于操控并能精确放置。然而,支架释放后显影性较差。此外,3例患者出现了手术并发症,包括支架移位(1例)和弹簧圈突入支架与血管壁之间(2例)。在后两例中,需要使用重塑球囊辅助弹簧圈的输送。当载瘤动脉直径大于4mm时,未观察到并发症的临床发生情况。血管造影结果包括8例完全闭塞、4例瘤颈残留和3例不完全闭塞。

结论

Enterprise支架在复杂颅内动脉瘤的血管内治疗中非常有用,因为它易于操控且能精确放置。然而,目前可用的支架有两个相对局限的特点:1)显影性较差;2)仅适用于位于最大直径为4mm的载瘤动脉上的动脉瘤。

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