Scheeres Korine, Wensing Michel, Severens Hans, Adang Eddy, Bleijenberg Gijs
Expert Centre Chronic Fatigue, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
J Psychosom Res. 2008 Jul;65(1):39-46. doi: 10.1016/j.jpsychores.2008.03.015. Epub 2008 May 22.
Chronic fatigue syndrome (CFS) is associated with a high use of health care services. To reduce the related costs for patients and society, it will be useful to know which factors determine CFS patients' amount of health care use. Little is known, however, about these factors.
The present study retrospectively performed a cross-sectional analysis to investigate the possible factors determining CFS patients' health care use. A total of 263 CFS patients, derived from two subgroups (149 from tertiary care and 114 from primary/secondary care), participated. Health care use was measured with a questionnaire asking details on consumption over the past 6 months. Fatigue severity and physical functioning were measured with the subscale Experienced Fatigue of the Checklist Individual Strength (CIS-20) and the subscale Physical Functioning of the SF-36, respectively. Multiple regression analysis, T-tests, and chi(2) tests were performed.
The regression analysis revealed that, after controlling for patient characteristics (explaining 13%), fatigue factors added 4% predictive value and certain perpetuating factors of fatigue, including focus on bodily symptoms and attributions of fatigue, added another 5%. The analysis of subgroups revealed that, compared to the tertiary care population, fewer patients from primary/secondary care had visited a medical specialist (50% vs. 71%), used antidepressants (16% vs. 25%) and tranquilizers (3% vs. 18%), and had spent a night in hospital (7% vs. 10%). However, overall costs of health care between these subgroups did not differ.
This study showed that illness duration, physical impairment due to fatigue, and psychological perpetuating factors of fatigue do determine the variance in CFS patients' health care use. These results give clear directions for treating CFS patients and managing health care for CFS.
慢性疲劳综合征(CFS)与大量使用医疗服务相关。为降低患者和社会的相关成本,了解哪些因素决定CFS患者的医疗服务使用量将很有帮助。然而,对于这些因素知之甚少。
本研究进行回顾性横断面分析,以调查决定CFS患者医疗服务使用的可能因素。共有263名CFS患者参与,他们来自两个亚组(149名来自三级医疗,114名来自初级/二级医疗)。通过问卷调查过去6个月的消费细节来衡量医疗服务使用情况。分别使用个体力量检查表(CIS-20)的“经历的疲劳”子量表和SF-36的“身体功能”子量表来测量疲劳严重程度和身体功能。进行了多元回归分析、T检验和卡方检验。
回归分析显示,在控制患者特征(解释13%)后,疲劳因素增加了4%的预测价值,而疲劳的某些持续因素,包括对身体症状的关注和疲劳归因,又增加了5%。亚组分析显示,与三级医疗人群相比,初级/二级医疗的患者中,看专科医生的较少(50%对71%),使用抗抑郁药的较少(16%对25%)和使用镇静剂的较少(3%对18%),住院过夜的也较少(7%对10%)。然而,这些亚组之间的总体医疗费用没有差异。
本研究表明,病程、疲劳导致的身体损伤以及疲劳的心理持续因素确实决定了CFS患者医疗服务使用的差异。这些结果为治疗CFS患者和管理CFS医疗服务提供了明确的方向。