Gorelik Oleg, Almoznino-Sarafian Dorit, Litvinov Vita, Alon Irena, Shteinshnaider Miriam, Dotan Eynat, Modai David, Cohen Natan
Department of Internal Medicine F, Assaf Harofeh Medical Center, affiliated to Sackler School of Medicine, Tel-Aviv University, Zerifin, Israel.
Gerontology. 2009;55(2):138-44. doi: 10.1159/000141920. Epub 2008 Jun 27.
Postural hypotension induced by transition from supine to sitting position and measures for its prevention in heart failure has not been investigated.
Our purpose was to evaluate the prevalence of postural hypotension and associated clinical manifestations as well as the contribution of various risk factors for postural hypotension on transition from lying to sitting in older patients with decompensated heart failure, and to study the eventual preventive effect of leg bandaging.
Seating-induced postural hypotension (>or=20 mm Hg systolic and/or >or=10 mm Hg diastolic blood pressure fall) was assessed on the first study day in 108 patients aged >or=60 years, hospitalized for acutely decompensated heart failure. On the next day, in patients manifesting postural hypotension, compression bandages were applied along both legs before seating. Blood pressure, heart rate, O(2) saturation, and the occurrence of dizziness or palpitations were recorded prior to and 1, 3 and 5 min following seating.
Postural hypotension occurred in 49.1% of patients. Dizziness and/or palpitations manifested in 25%. Diastolic (36.1%) versus systolic (23.1%) postural hypotension prevailed (p=0.05). On univariate analysis, postural hypotension was associated with female sex (p=0.03), more severe heart failure (p=0.05), longer bedrest (p=0.04), higher supine systolic (p=0.01) or diastolic (p=0.002) blood pressure, nonischemic heart failure (p=0.002), and not using nitrates (p = 0.01). On multivariate analysis, longer bedrest (OR=1.58, 95% CI=1.13-2.2, p<0.001), higher supine diastolic blood pressure (OR=1.33, 95% CI=1.1-1.61, p=0.001), and nonischemic heart failure (OR=3.48, 95% CI=1.4-8.63, p=0.009) were the most predictive of postural hypotension. Compression bandages prevented postural hypotension in 21 of 49 patients and decreased the degree of postural blood pressure fall (p<0.001).
Seating-induced postural hypotension is common among older inpatients with decompensated heart failure, especially with longer bedrest, higher supine diastolic blood pressure and non-ischemic etiology. Leg compression bandaging may be useful for the prevention of postural hypotension in these patients.
从仰卧位转变为坐位时诱发的体位性低血压及其在心力衰竭中的预防措施尚未得到研究。
我们的目的是评估体位性低血压的患病率及相关临床表现,以及老年失代偿性心力衰竭患者从卧位转变为坐位时体位性低血压的各种危险因素的作用,并研究腿部绑扎的最终预防效果。
在108例年龄≥60岁、因急性失代偿性心力衰竭住院的患者中,于研究的第1天评估坐位诱发的体位性低血压(收缩压下降≥20 mmHg和/或舒张压下降≥10 mmHg)。次日,对于出现体位性低血压的患者,在坐位前沿双腿应用加压绷带。记录坐位前及坐位后1、3和5分钟时的血压、心率、血氧饱和度以及头晕或心悸的发生情况。
49.1%的患者发生体位性低血压。25%的患者出现头晕和/或心悸。以舒张期(36.1%)体位性低血压为主,而非收缩期(23.1%)体位性低血压(p = 0.05)。单因素分析显示,体位性低血压与女性(p = 0.03)、更严重的心力衰竭(p = 0.05)、更长时间的卧床休息(p = 0.04)、较高的仰卧位收缩压(p = 0.01)或舒张压(p = 0.002)、非缺血性心力衰竭(p = 0.002)以及未使用硝酸盐(p = 0.01)有关。多因素分析显示,更长时间的卧床休息(OR = 1.58,95%CI = 1.13 - 2.2,p < 0.001)、较高的仰卧位舒张压(OR = 1.33,95%CI = 1.1 - 1.61,p = 0.001)和非缺血性心力衰竭(OR = 3.48,95%CI = 1.4 - 8.63,p = 0.009)是体位性低血压最具预测性的因素。加压绷带使49例患者中的21例预防了体位性低血压,并降低了体位性血压下降的程度(p < 0.001)。
坐位诱发的体位性低血压在老年失代偿性心力衰竭住院患者中很常见,尤其是在卧床休息时间较长、仰卧位舒张压较高且病因是非缺血性的患者中。腿部加压绑扎可能有助于预防这些患者出现体位性低血压。