Wang Yuanyuan, Han Zhenhui, Wang Yaru, Yan Yongqiang, Pan Zhitao, Zhu Hanwen, Li Hongxia, Tao Chunyan, Liu Ping, Wang Yuli, Tang Chaoshu, Jin Hongfang, Du Junbao
Department of Pediatrics, Peking University First Hospital, Beijing, China.
Department of Cardiology, Children's Hospital of Kaifeng, Henan, China.
PLoS One. 2022 Mar 18;17(3):e0265364. doi: 10.1371/journal.pone.0265364. eCollection 2022.
The study was designed to explore the risk factors for sitting-induced tachycardia syndrome (STS) in children and adolescents.
In this case-control study, 46 children with STS and 184 healthy children and adolescents were recruited. Demographic characteristics, lifestyle habits, allergy history, and family history were investigated using a questionnaire. The changes in heart rate and blood pressure from supine to sitting were monitored using a sitting test. The possible differences between STS patients and healthy children were analyzed using univariate analysis. Logistic regression analysis was used to explore the independent risk factors for STS. Univariate analysis showed that the daily sleeping time of the STS children were significantly shorter than that of the control group [(8.8 ± 1.2) hours/day vs. (9.3 ± 1.0) hours/day, P = 0.009], and the proportion of positive family history of syncope in the STS patients was higher than the controls (4/42 vs. 3/181, P = 0.044). Multivariate logistic regression studies showed that reduced daily sleeping time was an independent risk factor of STS in children (P = 0.006). Furthermore, when daily sleeping time was prolonged by 1 h, the risk of STS was decreased by 37.3%.
Reduced daily sleeping was an independent risk factor for STS in children and adolescents.
本研究旨在探讨儿童和青少年久坐诱发心动过速综合征（STS）的危险因素。
在这项病例对照研究中，招募了46例患有STS的儿童以及184例健康儿童和青少年。通过问卷调查来调查人口统计学特征、生活方式习惯、过敏史和家族史。使用坐位试验监测从仰卧位到坐位时心率和血压的变化。采用单因素分析来分析STS患者与健康儿童之间可能存在的差异。使用逻辑回归分析来探究STS的独立危险因素。单因素分析显示，STS儿童的每日睡眠时间显著短于对照组[（8.8±1.2）小时/天对（9.3±1.0）小时/天，P = 0.009]，并且STS患者中晕厥家族史阳性的比例高于对照组（4/42对3/181，P = 0.044）。多因素逻辑回归研究表明，每日睡眠时间减少是儿童发生STS的独立危险因素（P = 0.006）。此外，当每日睡眠时间延长1小时时，发生STS的风险降低37.3%。
每日睡眠时间减少是儿童和青少年发生STS的独立危险因素。
