Ribeiro Maria Elenir N P, de Oliveira Samira A, Ricardo Nágila M P S, Mai Shao-Min, Attwood David, Yeates Stephen G, Booth Colin
Department of Organic and Inorganic Chemistry, Polymer Laboratory, Federal University of Ceará, CX 12.200, CEP 60455-760 Fortaleza, Ceará, Brazil.
Int J Pharm. 2008 Oct 1;362(1-2):193-6. doi: 10.1016/j.ijpharm.2008.06.001. Epub 2008 Jun 7.
The dependence of log(cmc) on hydrophobic block length n was examined for E(m)B(n) copolymers (E=oxyethylene, B=oxybutylene, subscripts denote number-average block lengths in repeat units) with n in the range 30-76. Combination with published data for E(m)B(n) diblock copolymers with shorter E-blocks shows two changes of slope in the log(cmc)-n plot corresponding to the onset of unimolecular micelle formation at n approximately 12 and completion of this process at n approximately 30. The results are discussed with reference to published data for E(m)L(n) and E(m)CL(n) (L from d,L-lactide; CL from epsilon-caprolactone) copolymers, which show similar behaviour.
对于E(m)B(n)共聚物（E = 氧化乙烯，B = 氧化丁烯，下标表示重复单元中的数均嵌段长度），研究了log(cmc)对疏水嵌段长度n的依赖性，其中n的范围为30至76。与已发表的具有较短E嵌段的E(m)B(n)二嵌段共聚物的数据相结合，在log(cmc)-n图中显示出斜率的两个变化，分别对应于n约为12时单分子胶束形成的开始以及n约为30时该过程的完成。参考已发表的E(m)L(n)和E(m)CL(n)（L来自d,L-丙交酯；CL来自ε-己内酯）共聚物的数据对结果进行了讨论，这些共聚物表现出类似的行为。
