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子宫内膜癌的当前治疗策略。

Current treatment strategies for endometrial cancer.

作者信息

Fiorelli Jessica L, Herzog Thomas J, Wright Jason D

机构信息

Division of Gynecologic Oncology, Department of Obstetrics & Gynecology, Columbia University College of Physicians & Surgeons, The Herbert Irving Comprehensive Cancer Center, 161 Fort Washington Avenue, 8th Floor, NY 10032, USA.

出版信息

Expert Rev Anticancer Ther. 2008 Jul;8(7):1149-57. doi: 10.1586/14737140.8.7.1149.

Abstract

Treatment paradigms for endometrial cancer are rapidly evolving. New minimally invasive surgical techniques have helped to reduce the morbidity of women with early-stage tumors undergoing hysterectomy. A growing body of evidence has helped to stratify women with intermediate-risk endometrial cancer to optimize adjuvant therapy in this subset of patients. For women with high-risk and metastatic endometrial cancer there has been a renewed interest in incorporating chemotherapy into treatment paradigms. This review summarizes the latest advances in the treatment of endometrial cancer with a special focus on adjuvant therapy.

摘要

子宫内膜癌的治疗模式正在迅速演变。新的微创外科技术有助于降低早期肿瘤患者接受子宫切除术后的发病率。越来越多的证据有助于对中度风险子宫内膜癌患者进行分层,以优化这部分患者的辅助治疗。对于高危和转移性子宫内膜癌患者,将化疗纳入治疗模式重新引起了人们的兴趣。本综述总结了子宫内膜癌治疗的最新进展,特别关注辅助治疗。

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