Thursky K A, Playford E G, Seymour J F, Sorrell T C, Ellis D H, Guy S D, Gilroy N, Chu J, Shaw D R
Department of Infectious Diseases, Peter MacCallum Cancer Centre and St Vincent's Hospital, Melbourne, VIC.
Intern Med J. 2008 Jun;38(6b):496-520. doi: 10.1111/j.1445-5994.2008.01725.x.
Evidence-based guidelines for the treatment of established fungal infections in the adult haematology/oncology setting were developed by a national consensus working group representing clinicians, pharmacists and microbiologists. These updated guidelines replace the previous guidelines published in the Internal Medicine Journal by Slavin et al. in 2004. The guidelines are pathogen-specific and cover the treatment of the most common fungal infections including candidiasis, aspergillosis, cryptococcosis, zygomycosis, fusariosis, scedosporiosis, and dermatophytosis. Recommendations are provided for management of refractory disease or salvage therapies, and special sites of infections such as the cerebral nervous system and the eye. Because of the widespread use newer broad-spectrum triazoles in prophylaxis and empiric therapy, these guidelines should be implemented in concert with the updated prophylaxis and empiric therapy guidelines published by this group.
一个由临床医生、药剂师和微生物学家组成的全国性共识工作组制定了针对成人血液学/肿瘤学领域已确诊真菌感染的循证治疗指南。这些更新后的指南取代了斯拉文等人于2004年发表在《内科学杂志》上的先前指南。该指南针对特定病原体，涵盖了最常见真菌感染的治疗，包括念珠菌病、曲霉病、隐球菌病、接合菌病、镰刀菌病、赛多孢子菌病和皮肤癣菌病。指南还针对难治性疾病的管理或挽救治疗以及如中枢神经系统和眼部等特殊感染部位提供了建议。由于新型广谱三唑类药物在预防和经验性治疗中的广泛使用，这些指南应与该小组发布的更新后的预防和经验性治疗指南协同实施。
