Boulay A, Houghton J, Gancheva V, Sterk Y, Strada A, Schlegel-Zawadzka M, Sora B, Sala R, van Ree R, Rowe G
Institute of Food Research, Norwich Research Park, Colney, Norwich, UK.
Allergy. 2008 Jul;63(7):797-809. doi: 10.1111/j.1398-9995.2008.01776.x.
Peanuts are extensively cultivated around the world, providing a foodstuff that is both cheap to produce and nutritious. However, allergy to peanuts is of growing global concern, particularly given the severity of peanut-allergic reactions, which can include anaphylaxis and death. Consequently, it is important to understand the factors related to the prevalence of peanut allergy in order to inform efforts to ameliorate or pre-empt the condition. In this article we review evidence for the relevance of factors hypothesized to have some association with allergy prevalence, including both genetic and environmental factors. Although our analysis does indicate some empirical support for the importance of a number of factors, the key finding is that there are significant data gaps in the literature that undermine our ability to provide firm conclusions. We highlight these gaps, indicating questions that need to be addressed by future research.
花生在全球广泛种植，是一种生产成本低廉且营养丰富的食品。然而，花生过敏在全球范围内日益受到关注，尤其是考虑到花生过敏反应的严重性，其中可能包括过敏反应甚至死亡。因此，了解与花生过敏患病率相关的因素对于改善或预防这种情况的努力至关重要。在本文中，我们回顾了一些被认为与过敏患病率有某种关联的因素的相关证据，包括遗传和环境因素。尽管我们的分析确实表明了一些实证支持许多因素的重要性，但关键发现是文献中存在重大的数据缺口，这削弱了我们得出确凿结论的能力。我们强调这些缺口，并指出未来研究需要解决的问题。
