Osadchuk A M, Osadchuk M A, Kvetnoĭ I M
Klin Med (Mosk). 2008;86(5):33-8.
It is established, that chronic atrophic gastritis adenomatous polyps and gastric cancer are consecutive stages of gastric mucous tunic cell renovation disturbance, manifests itself in progressive delay its apoptosis activity from proliferation, which reflects increase in expression Ki-67 and Bcl-2. Eradication of Helicobacter pylori shorts activity and reduces intensity of inflammatory process in gastric mucous tunic and improves indices of cell renovation.
已经确定,慢性萎缩性胃炎、腺瘤性息肉和胃癌是胃黏膜层细胞更新紊乱的连续阶段,表现为其凋亡活性从增殖中逐渐延迟,这反映了Ki-67和Bcl-2表达的增加。根除幽门螺杆菌可缩短活性并降低胃黏膜层炎症过程的强度,并改善细胞更新指标。