Bhattacharyya S P, Sahu C
Anat Anz. 1976;140(1-2):162-9.
Intramuscular administration of cortisone acetate (5 mg daily to each for 15 days) to adult male pigeons provoked hypertrophy of the preen gland. Desquamation and loss of alveolar differentiated cells were also accelerated to a great extent. Significant changes observed in the histochemical composition of the alveoli of the preen gland of cortisone-treated pigeons were: (a) a greater accumulation of sudanophilic lipids within the alveoli, (b) an increase in the content of acidic lipids, (c) a decrease in the activity of acid phosphatase, and (d) an overall augmentation of the reaction for alkaline phosphatase. There was, however, no gross change in the activities of nonspecific esterases and lipase. The probable significance of the cortisone-induced glandular hypertrophy and histochemical changes has been briefly discussed.
对成年雄性鸽子肌肉注射醋酸可的松(每天每只5毫克,共15天)会引发尾脂腺肥大。肺泡分化细胞的脱屑和损失也在很大程度上加速。在接受可的松治疗的鸽子尾脂腺肺泡的组织化学组成中观察到的显著变化有:(a)肺泡内嗜苏丹脂质积累增多;(b)酸性脂质含量增加;(c)酸性磷酸酶活性降低;(d)碱性磷酸酶反应总体增强。然而,非特异性酯酶和脂肪酶的活性没有明显变化。本文简要讨论了可的松诱导的腺体肥大和组织化学变化的可能意义。