Daponte A, Kostopoulou E, Zavos A, Skentou H, Kallitsaris A, Koukoulis G, Messinis I E
Department of Obstetrics and Gynecology, University Hospital of Larissa, Greece.
Eur J Gynaecol Oncol. 2008;29(3):300-4.
The management of a Stage I immature teratoma during pregnancy with a review of the literature is reported.
A growing adnexal mass was removed at 12 weeks of gestation. Although the frozen section was negative, because of intraoperative clinical suspicion, a right salpingo-oophorectomy and surgical staging were performed. Histological examination revealed a Stage Ia, grade 1 immature ovarian teratoma. Appropriate surgical staging enabled avoidance of chemotherapy despite the unexpected histological diagnosis. The pregnancy was terminated because of fetal distress, with cesarean section at 34 weeks of gestation. At that time the peritoneal cavity was inspected and biopsies were taken as in second-look laparotomy. Two years after the first operation the patient remains disease free.
For adnexal masses removed during pregnancy frozen section is useful but when there is clinical suspicion surgical staging must be performed.
本文报告了孕期I期未成熟畸胎瘤的处理并复习相关文献。
孕12周时切除了一个不断增大的附件包块。尽管冰冻切片结果为阴性，但由于术中临床怀疑，遂行右侧输卵管卵巢切除术及手术分期。组织学检查显示为Ia期1级未成熟卵巢畸胎瘤。尽管组织学诊断出乎意料，但合适的手术分期避免了化疗。因胎儿窘迫，于孕34周行剖宫产终止妊娠。当时对腹腔进行了检查并像二次探查剖腹术一样取了活检。首次手术后两年，患者仍无疾病复发。
对于孕期切除的附件包块，冰冻切片有用，但当有临床怀疑时必须进行手术分期。
