Mitra Biswadev, Cameron Peter A, Gabbe Belinda J, Rosenfeld Jeffrey V, Kavar Bhadrakant
Emergency & Trauma Centre, The Alfred Hospital, Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
ANZ J Surg. 2008 Jul;78(7):588-92. doi: 10.1111/j.1445-2197.2008.04579.x.
Severe traumatic head injury in the elderly has been associated with poor outcomes. However, there is currently no consensus to direct management in these patients. This study outlines the demographics, injury characteristics, management and outcome of the elderly trauma patients with severe head injury across a defined population.
A retrospective review of all elderly patients (age >64 years) with a Glasgow Coma Scale (GCS) score of 8 or less, and confirmed intracranial pathology or fractured skull, was undertaken over a period of 40 months from July 2001 to September 2005. Data on patient demographics, injury cause, presenting clinical features and interventions were collected. In-hospital mortality was used as the primary outcome.
There were 96 patients who met the inclusion criteria. One-third of the patients were managed palliatively, one-third supportively without surgery and another third underwent surgery. Overall mortality was 70.8% (n = 68). Older age and brainstem injuries were identified as independent predictors of mortality. Mortality was reported in all patients aged 85 years or older.
Although overall outcomes were poor, careful consideration should be given to active treatment as favourable outcomes were possible even in the presence of extremely low GCS scores. Prediction of outcome on the basis of age and anatomical diagnoses may help in this decision-making.
老年人严重创伤性脑损伤与不良预后相关。然而,目前对于这些患者的治疗尚无共识。本研究概述了特定人群中重度颅脑损伤老年创伤患者的人口统计学特征、损伤特点、治疗及预后情况。
对2001年7月至2005年9月期间40个月内所有格拉斯哥昏迷量表(GCS)评分≤8分且确诊有颅内病变或颅骨骨折的老年患者(年龄>64岁)进行回顾性研究。收集患者的人口统计学数据、损伤原因、临床表现及干预措施。以院内死亡率作为主要结局指标。
96例患者符合纳入标准。三分之一的患者接受姑息治疗,三分之一接受非手术支持治疗,另有三分之一接受手术治疗。总体死亡率为70.8%(n = 68)。年龄较大和脑干损伤被确定为死亡率的独立预测因素。所有85岁及以上患者均报告死亡。
尽管总体预后不佳,但应谨慎考虑积极治疗,因为即使GCS评分极低,也有可能获得良好预后。根据年龄和解剖诊断预测预后可能有助于做出这一决策。