Farris Karen B, Phillips Beth Bryles
Division of Clinical and Administrative Pharmacy, College of Pharmacy, University of Iowa, Iowa City, IA 52242, USA.
Ann Pharmacother. 2008 Jul;42(7):1026-36. doi: 10.1345/aph.1G502. Epub 2008 Jul 1.
To review literature on instruments available for assessing the physical and cognitive ability to take medications as prescribed, which serve as a way to rule out reasons for nonadherence.
A PubMed search (1950-February 2008) was conducted to identify relevant articles. Additional references were obtained from cross-referencing the bibliographies of selected articles. Only journals containing English-language articles were selected for review.
Articles that described a simulated assessment of medication management were obtained, irrespective of whether the assessment also contained data about medication adherence or was focused on older adults.
Fifteen instruments were identified. Six instruments required 5 minutes or less to administer, 5 required 6-30 minutes, and 4 had no administration time data reported. A possible advantage of 3 of the instruments is that they use a subject's own medications and may therefore provide a more authentic assessment. Only 2 instruments have been tested by subjects other than the drug developers and only one has been used in 2 different populations, thereby affording some insight into generalizability. These studies have used a variety of other validated surveys/assessments to provide an indication of construct validity, including neuropsychological batteries, caregiver reports, prospective outcomes, instrumental activities of daily living, and levels of care. One instrument determined whether individuals could tell if refills existed, whom to contact, and resources to obtain medications. Three assessed numeracy literacy.
Five instruments that measure medication management capacity should be compared for potential further use, including Beckman's tasks, due to their brevity and assessment of numeracy literacy; the Medication Management Ability Assessment, Drug Regimen Unassisted Grading Scale, and Hopkins Medication Schedule because of the evidence supporting their use; and the Medication Management Instrument for Deficiencies in the Elderly because it includes an assessment of the patient's knowledge of how to obtain more medications. No brief tool is available for the primary care setting to identify individuals with medication management problems or to guide the type and amount of support required to manage medications.
回顾关于可用于评估按处方服药的身体和认知能力的工具的文献,这些工具可作为排除不依从原因的一种方式。
进行了一项PubMed搜索(1950年 - 2008年2月)以识别相关文章。通过对所选文章的参考文献进行交叉引用获得了其他参考文献。仅选择包含英文文章的期刊进行综述。
获取了描述药物管理模拟评估的文章,无论该评估是否还包含有关药物依从性的数据或是否针对老年人。
识别出15种工具。6种工具的实施时间为5分钟或更短,5种需要6 - 30分钟,4种未报告实施时间数据。其中3种工具的一个可能优势是它们使用受试者自己的药物,因此可能提供更真实的评估。只有2种工具在药物开发者以外的受试者中进行了测试,只有1种在2个不同人群中使用过,从而对普遍性有了一些了解。这些研究使用了各种其他经过验证的调查/评估来提供结构效度的指标,包括神经心理测试组、照顾者报告、前瞻性结果、日常生活工具性活动和护理水平。一种工具确定个体是否能知道是否有续方、联系谁以及获取药物的资源。三种评估数字素养。
应比较五种测量药物管理能力的工具以便可能进一步使用,包括贝克曼任务,因其简短且评估数字素养;药物管理能力评估、药物治疗方案无辅助分级量表和霍普金斯药物时间表,因为有证据支持其使用;以及老年人药物管理缺陷工具,因为它包括对患者如何获取更多药物知识的评估。在初级保健环境中,没有简短的工具可用于识别有药物管理问题的个体或指导管理药物所需的支持类型和数量。