Da Settimo A, Marini A M, Primofiore G, Subissi A
Istituto di Chimica Farmaceutica dell'Università di Pisa, Italy.
Farmaco. 1991 Feb;46(2):357-67.
The synthesis of some 2-aminobenzimidazole and indole amide derivatives containing a 2,6-dichloroaniline moiety is described. The preparation of a theophylline derivative is also reported. All the compounds tested showed no appreciable antihypertensive activity on spontaneously hypertensive rats.
描述了一些含有2,6-二氯苯胺部分的2-氨基苯并咪唑和吲哚酰胺衍生物的合成。还报道了一种茶碱衍生物的制备。所有测试的化合物对自发性高血压大鼠均未显示出明显的降压活性。