Jacobsson S, Karlsson G, Rignér P, Sanner E, Schrewelius C
ENT Department, Mölndal Hospital, Sweden.
Eur Arch Otorhinolaryngol. 1991;248(4):246-9. doi: 10.1007/BF00173665.
Sixty patients with mild to moderate forms of eczematous otitis externa were treated with budesonide and placebo in a double-blind controlled study using parallel groups. Each treatment period was preceded by otomicroscopic examination and thorough cleaning of the ear canal. The symptoms and signs were assessed with a score system ranging from 0 (no symptoms/signs) to 3 (severe symptoms/signs). Budesonide treatment was associated with a reduction in severity of all symptoms recorded and a marked improvement in erythema, swelling and discharge. Mechanical cleaning of the ear canal and placebo was not a sufficient treatment for this group of patients.
在一项采用平行组的双盲对照研究中，60例轻至中度湿疹性外耳道炎患者接受了布地奈德和安慰剂治疗。每个治疗阶段之前均进行耳镜检查并彻底清洁耳道。症状和体征采用评分系统评估，范围从0（无症状/体征）至3（严重症状/体征）。布地奈德治疗与所记录的所有症状严重程度降低以及红斑、肿胀和分泌物显著改善相关。对于该组患者，耳道机械清洁和安慰剂治疗并不充分。
