Kitchen Marcus J, Pavlov Konstantin M, Hooper Stuart B, Vine David J, Siu Karen K W, Wallace Megan J, Siew Melissa L L, Yagi Naoto, Uesugi Kentaro, Lewis Rob A
School of Physics, Monash University, Victoria 3800, Australia.
Eur J Radiol. 2008 Dec;68(3 Suppl):S49-53. doi: 10.1016/j.ejrad.2008.04.028. Epub 2008 Jul 2.
Analyser-based phase contrast X-ray imaging can provide high-contrast images of biological tissues with exquisite sensitivity to the boundaries between tissues. The phase and absorption information can be extracted by processing multiple images acquired at different analyser orientations. Recording both the transmitted and diffracted beams from a thin Laue analyser crystal can make phase retrieval possible for dynamic systems by allowing full field imaging. This technique was used to image the thorax of a mechanically ventilated newborn rabbit pup using a 25 keV beam from the SPring-8 synchrotron radiation facility. The diffracted image was produced from the (111) planes of a 50 mm x 40 mm, 100 microm thick Si analyser crystal in the Laue geometry. The beam and analyser were large enough to image the entire chest, making it possible to observe changes in anatomy with high contrast and spatial resolution.
基于分析仪的相衬X射线成像能够提供生物组织的高对比度图像，对组织间边界具有极高的敏感度。通过处理在不同分析仪取向采集的多幅图像，可以提取相位和吸收信息。记录来自薄劳厄分析仪晶体的透射光束和衍射光束，通过全场成像可实现动态系统的相位检索。利用来自SPring-8同步辐射装置的25 keV光束，该技术被用于对机械通气的新生兔崽的胸部进行成像。衍射图像由处于劳厄几何构型的一块50 mm×40 mm、100微米厚的硅分析仪晶体的（111）平面产生。光束和分析仪足够大，能够对整个胸部进行成像，从而有可能以高对比度和空间分辨率观察解剖结构的变化。
