Sven Gathmann, Eva Rupprecht, Uwe Kahmann, Schneider Dirk
Institut für Biochemie und Molekularbiologie, Zentrum für Biochemie und Molekulare Zellforschung, Albert-Ludwigs-Universität, Stefan-Meier-Strasse 19, Freiburg, Germany.
J Microbiol Biotechnol. 2008 Jun;18(6):1090-4.
In this article, we show that the orf slr1471 from Synechocystis sp. PCC 6803 codes for a functional member of the YidC/Alb3/Oxa1 protein family, and the encoded protein has a transmembrane topology with a common core structure. Using specific antibodies raised against the Synechocystis YidC homologous protein, we further show that the Synechocystis YidC protein appears to be predominantly localized in the cyanobacterial cytoplasmic membrane. The impact of the described findings for synthesis of membrane proteins and for protein sorting within cyanobacterial cells is discussed.
在本文中，我们表明来自集胞藻PCC 6803的orf slr1471编码YidC/Alb3/Oxa1蛋白家族的一个功能成员，并且所编码的蛋白质具有带有共同核心结构的跨膜拓扑结构。使用针对集胞藻YidC同源蛋白产生的特异性抗体，我们进一步表明集胞藻YidC蛋白似乎主要定位于蓝细菌的细胞质膜中。讨论了所描述的发现对蓝细菌细胞内膜蛋白合成和蛋白质分选的影响。
