Westbury H A, Sinkovic B
Aust Vet J. 1976 Aug;52(8):374-7. doi: 10.1111/j.1751-0813.1976.tb09492.x.
An immune response was induced in chickens vaccinated with the NSW-1 virus by the intramuscular, eye drop, wing web or oral methods. The oral procedure was the most sensitive in inducing an immune response with the lowest dose of virus. The wing web method was the least sensitive. Clinical IAE developed in 1 chicken following intramuscular vaccination. The virus was recovered from the faeces of chickens vaccinated orally with 700 CID50 of the virus from the third to the tenth day after vaccination.
通过肌肉注射、滴眼、翼膜接种或口服方法,用NSW - 1病毒对鸡进行疫苗接种后可诱导免疫反应。口服接种程序在使用最低剂量病毒时诱导免疫反应最为敏感。翼膜接种方法最不敏感。肌肉注射疫苗接种后有1只鸡出现了临床传染性关节炎脑炎(IAE)。在接种700个半数鸡胚感染剂量(CID50)病毒的鸡口服接种疫苗后的第三天至第十天,从其粪便中分离到了病毒。