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社会经济地位对重症患者预后的影响:一项关联数据队列研究。

The effect of socioeconomic status on outcomes for seriously ill patients: a linked data cohort study.

作者信息

Ho Kwok M, Dobb Geoffrey J, Knuiman Matthew, Finn Judith, Webb Steven A

机构信息

Royal Perth Hospital, Perth, WA, Australia.

出版信息

Med J Aust. 2008 Jul 7;189(1):26-30. doi: 10.5694/j.1326-5377.2008.tb01890.x.

Abstract

OBJECTIVE

To investigate the association between socioeconomic status (SES) and outcomes for seriously ill patients.

DESIGN AND SETTING

A retrospective cohort study based on data from an intensive care unit clinical database linked with data from the Western Australian hospital morbidity and mortality databases over a 16-year period (1987-2002).

MAIN OUTCOME MEASURES

In-hospital and long-term mortality.

RESULTS

Data on 15,619 seriously ill patients were analysed. The in-hospital mortality rate for all seriously ill patients was 14.8%, and the incidence of death after critical illness was 7.4 per 100 person-years (4.8 per 100 person-years after hospital discharge). Patients from the most socioeconomically disadvantaged areas were more likely to be younger, to be Indigenous, to live in a remote area, to be admitted non-electively, and to have more severe acute disease and comorbidities. SES was not significantly associated with in-hospital mortality, but long-term mortality was significantly higher in patients from the lowest SES group than in those from the highest SES group, after adjusting for age, ethnicity, comorbidities, severity of acute illness, and geographical accessibility to essential services (hazard ratio for death in lowest SES group v highest SES group was 1.21 [95% CI, 1.04-1.41]; P = 0.014). The attributable incidence of death after hospital discharge between patients from the lowest and highest SES groups was 1.0 per 100 person-years (95% CI, 0.3-1.6 per 100 person-years).

CONCLUSION

Lower SES was associated with worse long-term survival after critical illness over and above the background effects of age, acuity of acute illness, comorbidities, Indigenous status and geographical access to essential services.

摘要

目的

探讨社会经济地位(SES)与重症患者预后之间的关联。

设计与背景

一项回顾性队列研究,基于重症监护病房临床数据库的数据,并与西澳大利亚医院发病率和死亡率数据库的数据相链接,研究时间跨度为16年(1987 - 2002年)。

主要观察指标

住院期间及长期死亡率。

结果

分析了15619例重症患者的数据。所有重症患者的住院死亡率为14.8%,危重症后的死亡发生率为每100人年7.4例(出院后每100人年4.8例)。社会经济地位最不利地区的患者更可能较年轻、为原住民、居住在偏远地区、非选择性入院,且患有更严重的急性疾病和合并症。SES与住院死亡率无显著关联,但在调整年龄、种族、合并症、急性疾病严重程度以及获得基本服务的地理可达性后,SES最低组患者的长期死亡率显著高于最高组(SES最低组与最高组的死亡风险比为1.21 [95%CI,1.04 - 1.41];P = 0.014)。SES最低组与最高组患者出院后死亡的归因发病率为每100人年1.0例(95%CI,每100人年0.3 - 1.6例)。

结论

除年龄、急性疾病严重程度、合并症、原住民身份以及获得基本服务的地理可达性等背景因素外,较低的SES与危重症后较差的长期生存相关。

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