Shinjo Samuel Katsuyuki, Hasegawa Eduardo Massato, Costa Malheiros Denise Maria Avancini, Levy-Neto Mauricio
Disciplina da Reumatologia, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brasil.
Acta Reumatol Port. 2008 Apr-Jun;33(2):220-3.
Goodpasture s syndrome (GS) is an auto-immune disease that is part of the pulmonary-renal syndrome spectrum. It is characterized by the linear deposition of anti-glomerular basement membrane antibodies (anti-GBM) in glomerular and alveolar basement membrane resulting in alveolar hemorrhage and progressive glomerulonephritis. An early diagnosis is important to decrease clinical morbidity. In the present work we illustrate a GS case initially diagnosed as Wegener s granulomatosis. The patient showed favorable clinical evolution with corticosteroid therapy associated with plasmapheresis and cyclophosphamide.
肺出血肾炎综合征（GS）是一种自身免疫性疾病，属于肺肾综合征范畴。其特征是抗肾小球基底膜抗体（抗GBM）在肾小球和肺泡基底膜呈线性沉积，导致肺泡出血和进行性肾小球肾炎。早期诊断对于降低临床发病率很重要。在本研究中，我们阐述了一例最初被诊断为韦格纳肉芽肿的GS病例。该患者在接受皮质类固醇治疗并联合血浆置换和环磷酰胺后，临床病情呈良好进展。
