Pollatos Olga, Herbert Beate M, Schandry Rainer, Gramann Klaus
Department of Neurology, Ludwig-Maximilians-University of Munich, Germany.
Psychosom Med. 2008 Jul;70(6):701-8. doi: 10.1097/PSY.0b013e31817e41e6.
To elucidate the potential relationship between classification of emotional faces and impaired central processing in eating disorders and to investigate the potential mediatory role of alexithymia and depression in this relationship.
Visual-evoked potentials (VEPs) to emotional faces and classification performance were assessed in 12 anorexic females and matched healthy controls.
Patients with anorexia nervosa showed no modulation of emotional face processing and displayed significantly increased N200 amplitudes in response to all emotional categories and decreased VEPs in response to unpleasant emotional faces in the P300 time range as compared with healthy controls. They also made more mistakes in emotional face recognition, in particular, for neutral, sad, and disgusted content.
There are marked differences in evoked potentials and emotion recognition performances of patients with anorexia nervosa and controls in facial processing. Differences in brain dynamics might contribute to difficulties in the correct recognition of facially expressed emotions, deficits in social functioning, and in turn the maintenance of eating disorders.
阐明饮食失调中情绪面孔分类与中枢加工受损之间的潜在关系，并研究述情障碍和抑郁在这种关系中的潜在中介作用。
对12名神经性厌食症女性患者及匹配的健康对照者进行了针对情绪面孔的视觉诱发电位（VEP）和分类表现评估。
与健康对照者相比，神经性厌食症患者对情绪面孔加工无调节作用，对所有情绪类别面孔的反应中N200波幅显著增加，在P300时间范围内对不愉快情绪面孔的VEP降低。他们在情绪面孔识别中也犯了更多错误，尤其是对于中性、悲伤和厌恶内容的面孔。
神经性厌食症患者与对照者在面部加工的诱发电位和情绪识别表现上存在显著差异。脑动力学差异可能导致正确识别面部表情情绪困难、社交功能缺陷，进而导致饮食失调持续存在。
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