Katz Itamar, Low-Beer Daniel
Health and Population Evaluation Unit, Cambridge University, Cambridge, United Kingdom.
Sex Transm Dis. 2008 Oct;35(10):837-42. doi: 10.1097/OLQ.0b013e31817c0be5.
To understand the stabilization in HIV prevalence in South Africa, and why HIV prevalence has not declined further, despite behavior change and apparently moderate risk behaviors.
HIV prevalence and 4 HIV-related sexual behaviors in 15- to 24-year old South Africans and Ugandans were compared, before and during HIV prevalence stabilization and decrease, respectively.
According to standard indicators, 15- to 24-year-old South Africans have shown behavior change and have moderate risk behaviors. Yet, the HIV prevalence of South African youth is more than twice the prevalence among Ugandan youth, despite 2 times greater reported condom use and an increase in secondary abstinence among young females. We observed inconsistent use of condoms and an extended age distribution of risk together with age and partner mixing. These increase the cumulative risk beyond indicators which are based on sexual behavior in the last year and condom use at last sexual act. In addition, the extended age distribution of risk together with age and partner mixing, increase the cumulative risk beyond standard indicators which are based on sexual behavior in the last year and condom use at last sexual act.
Comprehensive HIV prevention in South Africa needs to be intensified beyond individual age groups for example youth, clearly promote consistent condom use and reduction in sexual partners, and focus on the transmission dynamics including older age groups. This should be based on careful behavioral analysis of the epidemic, which goes beyond standard indicators. This study shows the significant risks beyond apparently improving behavioral indicators in Southern Africa, and helps explains the seriousness of the epidemics in this region.
了解南非艾滋病毒流行率的稳定情况,以及尽管行为发生了改变且危险行为明显有所缓和,但艾滋病毒流行率为何没有进一步下降。
分别比较了南非和乌干达15至24岁人群在艾滋病毒流行率稳定期和下降期之前及期间的艾滋病毒流行率以及4种与艾滋病毒相关的性行为。
根据标准指标,15至24岁的南非人已表现出行为改变且危险行为处于中等水平。然而,南非青年的艾滋病毒流行率是乌干达青年的两倍多,尽管报告的避孕套使用率高出两倍,且年轻女性的二次禁欲有所增加。我们观察到避孕套使用不一致、危险行为的年龄分布范围扩大以及年龄和性伴混合情况。这些因素增加了累积风险,超出了基于去年性行为和最后一次性行为时避孕套使用情况的指标。此外,危险行为的年龄分布范围扩大以及年龄和性伴混合情况,增加了累积风险,超出了基于去年性行为和最后一次性行为时避孕套使用情况的标准指标。
南非的全面艾滋病毒预防工作需要在各个年龄组(例如青年组)之外进一步加强,明确促进避孕套的持续使用并减少性伴侣数量,并关注包括老年组在内的传播动态。这应基于对该流行病的仔细行为分析,而不仅仅局限于标准指标。本研究显示了在南部非洲,表面上行为指标有所改善但仍存在的重大风险,并有助于解释该地区疫情的严重性。