Hargreaves J R, Morison L A, Kim J C, Bonell C P, Porter J D H, Watts C, Busza J, Phetla G, Pronyk P M
Infectious Disease Epidemiology Unit, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK.
J Epidemiol Community Health. 2008 Feb;62(2):113-9. doi: 10.1136/jech.2006.053827.
To investigate whether the prevalence of HIV infection among young people, and sexual behaviours associated with increased HIV risk, are differentially distributed between students and those not attending school or college.
A random population sample of unmarried young people (916 males, 1003 females) aged 14-25 years from rural South Africa in 2001.
Data on school attendance and HIV risk characteristics came from structured face-to-face interviews. HIV serostatus was assessed by oral fluid ELISA. Logistic regression models specified HIV serostatus and high-risk behaviours as outcome variables. The primary exposure was school attendance. Models were adjusted for potential confounders.
HIV knowledge, communication about sex and HIV testing were similarly distributed among students and non-students. The lifetime number of partners was lower for students of both sexes (adjusted odds ratio (aOR) for more than three partners for men 0.67; 95% CI 0.44 to 1.00; aOR for more than two partners for women 0.69; 95% CI 0.46 to 1.04). Among young women, fewer students reported having partners more than three years older than themselves (aOR 0.58; 95% CI 0.37 to 0.92), having sex more than five times with a partner (aOR 0.57; 95% CI 0.37 to 0.87) and unprotected intercourse during the past year (aOR 0.60; 95% CI 0.40 to 0.91). Male students were less likely to be HIV positive than non-students (aOR 0.21; 95% CI 0.06 to 0.71).
Attending school was associated with lower-risk sexual behaviours and, among young men, lower HIV prevalence. Secondary school attendance may influence the structure of sexual networks and reduce HIV risk. Maximising school attendance may reduce HIV transmission among young people.
调查年轻人中艾滋病毒感染率以及与艾滋病毒风险增加相关的性行为在学生和未上学或未上大学的人群中分布是否存在差异。
2001年从南非农村地区抽取的14至25岁未婚年轻人的随机人口样本(916名男性,1003名女性)。
关于上学情况和艾滋病毒风险特征的数据来自结构化面对面访谈。通过口腔液酶联免疫吸附测定法评估艾滋病毒血清状态。逻辑回归模型将艾滋病毒血清状态和高危行为指定为结果变量。主要暴露因素是上学情况。模型针对潜在混杂因素进行了调整。
艾滋病毒知识、关于性和艾滋病毒检测的交流在学生和非学生中分布相似。男女学生的终身性伴侣数量较少(男性有三个以上伴侣的调整优势比(aOR)为0.67;95%置信区间为0.44至1.00;女性有两个以上伴侣的aOR为0.69;95%置信区间为0.46至1.04)。在年轻女性中,较少学生报告其伴侣比自己大三岁以上(aOR为0.58;95%置信区间为0.37至0.92)、与伴侣发生性行为超过五次(aOR为0.57;95%置信区间为0.37至0.87)以及在过去一年中有无保护性行为(aOR为0.60;95%置信区间为0.40至0.91)。男学生感染艾滋病毒呈阳性的可能性低于非学生(aOR为0.21;95%置信区间为0.06至0.71)。
上学与低风险性行为相关,并且在年轻男性中,艾滋病毒感染率较低。中学入学率可能会影响性网络结构并降低艾滋病毒风险。提高入学率可能会减少年轻人中的艾滋病毒传播。