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用于胸壁畸形放射学评估的自动化新指标的开发及其定量评估。

Development of automatized new indices for radiological assessment of chest-wall deformity and its quantitative evaluation.

作者信息

Kim H C, Park H J, Ham S Y, Nam K W, Choi S Y, Oh J S, Choi H, Jeong G S, Park S W, Kim M G, Sun K

机构信息

Department of Biomedical Engineering, Brain Korea 21 Project for Biomedical Science, College of Medicine, Korea University, Seoul, South Korea.

出版信息

Med Biol Eng Comput. 2008 Aug;46(8):815-23. doi: 10.1007/s11517-008-0367-2. Epub 2008 Jul 9.

Abstract

Pre-operative diagnosis of chest-wall deformity is important for successful surgical correction and post-operative evaluation of funnel chest patients. However, conventional indices that define the severity of deformity have several limitations; manually calculated and cannot supply information about asymmetry. We developed four indices that can represent both the depression and the asymmetry of the chest-wall, and can automatically be extracted by computerized image processing technique. Three indices, including eccentricity index (EI), flatness index (FI), and circularity index (CI), were suggested to represent the depression of the chest-wall, and one index, rotation index (RI), to represent the asymmetry of the chest-wall. To verify the feasibility of new indices, several synthetic images and real CT images were used to analyze the performance of new indices and the statistical relationship with conventional Haller index. The experimental results showed possible application of suggested indices to the diagnosis of funnel chest patient. Suggested indices showed clear trends of change with the severity of chest-wall deformation in regards to both the depression and the asymmetry. Results of statistical analysis showed high correlation between new indices and HI, showing possibility of replacing HI.

摘要

术前诊断胸壁畸形对于漏斗胸患者手术矫正的成功及术后评估很重要。然而,用于定义畸形严重程度的传统指标存在若干局限性;需手动计算且无法提供关于不对称性的信息。我们开发了四个能够同时体现胸壁凹陷和不对称性的指标,并且可以通过计算机图像处理技术自动提取。提出了三个指标,包括偏心率指数(EI)、平坦度指数(FI)和圆度指数(CI),用于表示胸壁的凹陷程度,还有一个指标,旋转指数(RI),用于表示胸壁的不对称性。为验证新指标的可行性,使用了若干合成图像和真实CT图像来分析新指标的性能以及与传统哈勒指数的统计关系。实验结果表明所提出的指标在漏斗胸患者诊断中具有应用可能性。所提出的指标在胸壁凹陷和不对称性方面均随胸壁变形严重程度呈现出明显的变化趋势。统计分析结果表明新指标与哈勒指数高度相关,显示出替代哈勒指数的可能性。

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