Scott Lyne, Nichols Breck, Choi Kwong Kenny Yat, Morphew Tricia, Jones Craig A
Department of Pediatrics, Division of Allergy and Immunology, University of Southern California Medical Center, Los Angeles County, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
J Asthma. 2008 Aug;45(6):501-5. doi: 10.1080/02770900802085477.
To determine if patterns of predominant asthma disease activity are more closely related than baseline asthma severity to measures of morbidity (acute asthma attack, emergency room visit/hospitalization, missed school days, and/or steroid burst). Retrospective analysis was performed for inner-city Los Angeles asthmatic children (3 to 18 years of age) during their first year of enrollment in an asthma-specific disease management program. All measures of morbidity were more closely related to patterns of predominant disease activity than baseline severity. We conclude that patterns of predominant disease activity are a more significant predictor of asthma morbidity than is baseline severity.
为了确定相较于哮喘基线严重程度,哮喘主要疾病活动模式是否与发病指标(急性哮喘发作、急诊就诊/住院、缺课天数和/或类固醇冲击治疗)的相关性更强。对洛杉矶市中心哮喘患儿(3至18岁)在参加特定哮喘疾病管理项目的第一年进行了回顾性分析。所有发病指标与主要疾病活动模式的相关性均强于基线严重程度。我们得出结论,相较于基线严重程度,主要疾病活动模式是哮喘发病更重要的预测指标。