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面神经增强MRI定量分析在贝尔面瘫中的临床意义

Clinical significance of quantitative analysis of facial nerve enhancement on MRI in Bell's palsy.

作者信息

Song Mee Hyun, Kim Jinna, Jeon Ju Hyun, Cho Chang Il, Yoo Eun Hye, Lee Won-Sang, Lee Ho-Ki

机构信息

Department of Otorhinolaryngology, Myongji Hospital, Kwandong University College of Medicine, Goyang, Korea.

出版信息

Acta Otolaryngol. 2008 Nov;128(11):1259-65. doi: 10.1080/00016480801901659.

DOI:10.1080/00016480801901659
PMID:18618345
Abstract

CONCLUSIONS

Quantitative analysis of the facial nerve on the lesion side as well as the normal side, which allowed for more accurate measurement of facial nerve enhancement in patients with facial palsy, showed statistically significant correlation with the initial severity of facial nerve inflammation, although little prognostic significance was shown.

OBJECTIVES

This study investigated the clinical significance of quantitative measurement of facial nerve enhancement in patients with Bell's palsy by analyzing the enhancement pattern and correlating MRI findings with initial severity of facial palsy and clinical outcome.

SUBJECTS AND METHODS

Facial nerve enhancement was measured quantitatively by using the region of interest on pre- and postcontrast T1-weighted images in 44 patients diagnosed with Bell's palsy. The signal intensity increase on the lesion side was first compared with that of the contralateral side and then correlated with the initial degree of facial palsy and prognosis.

RESULTS

The lesion side showed significantly higher signal intensity increase compared with the normal side in all of the segments except for the mastoid segment. Signal intensity increase at the internal auditory canal and labyrinthine segments showed correlation with the initial degree of facial palsy but no significant difference was found between different prognostic groups.

摘要

结论

对面神经病变侧及正常侧进行定量分析,能够更准确地测量面瘫患者面神经强化情况,结果显示其与面神经炎症的初始严重程度存在统计学显著相关性,尽管预后意义不大。

目的

本研究通过分析强化模式并将MRI表现与面瘫的初始严重程度及临床结局相关联,探讨贝尔面瘫患者面神经强化定量测量的临床意义。

对象与方法

对44例诊断为贝尔面瘫的患者,利用对比剂注射前后T1加权图像上的感兴趣区对面神经强化进行定量测量。首先将病变侧的信号强度增加与对侧进行比较,然后与面瘫的初始程度及预后相关联。

结果

除乳突段外,病变侧在所有节段的信号强度增加均显著高于正常侧。内听道段和迷路段的信号强度增加与面瘫的初始程度相关,但不同预后组之间未发现显著差异。

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