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免疫性血小板减少性紫癜作为汉赛巴尔通体感染的一种并发症。

Immune thrombocytopenic purpura as a complication of Bartonella henselae infection.

作者信息

Palumbo Emilio, Sodini Federica, Boscarelli Giuseppe, Nasca Giuseppina, Branchi Maurizio, Pellegrini Guido

机构信息

Dipartimento di Pediatria, Ospedale di Sondrio, Sondrio, Italy.

出版信息

Infez Med. 2008 Jun;16(2):99-102.

Abstract

Immune thrombocytopenic purpura is an infrequent yet well-recognized complication of viral infections, such as mumps, rubella, varicella, cytomegalovirus, parvovirus and infectious monunucleosis by Epstein-Barr virus. Some recent studies have described a possible association between Henoch-Schonlein purpura, a non-thrombocytopenic purpura, and seropositivity for Bartonella henselae, but in the literature only sporadic case reports have described a severe immune thrombocytopenic purpura as a complication of Bartonella henselae infection. We report a case of an immunocompetent child with clinical and serological evidence of Bartonella henselae infection presenting with purpura and cervical lymphoadenopathy and treated with intravenous immunoglobulin. The patient obtained a rapid and persistent increase in platelet count and a complete regression of purpura.

摘要

免疫性血小板减少性紫癜是病毒感染(如腮腺炎、风疹、水痘、巨细胞病毒、细小病毒和爱泼斯坦-巴尔病毒引起的传染性单核细胞增多症)一种虽不常见但已得到充分认识的并发症。最近一些研究描述了一种非血小板减少性紫癜——亨诺赫-舍恩莱因紫癜与汉赛巴尔通体血清阳性之间可能存在的关联,但文献中仅有零星病例报告描述了严重免疫性血小板减少性紫癜作为汉赛巴尔通体感染的一种并发症。我们报告了一例具有免疫功能的儿童,有汉赛巴尔通体感染的临床和血清学证据,表现为紫癜和颈部淋巴结病,并接受了静脉注射免疫球蛋白治疗。该患者血小板计数迅速且持续升高,紫癜完全消退。

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