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[上皮样肉瘤——一种被忽视的诊断?]

[Epitheloid sarcoma--an overlooked diagnosis?].

作者信息

Jensen D B, Nielsen N H, Nielsen P L, Krag C

机构信息

Københavns Amts Sygehus i Gentofte, plastikkirurgisk afdeling.

出版信息

Ugeskr Laeger. 1991 Jun 24;153(26):1873-4.

PMID:1862573
Abstract

Epitheloid sarcoma (ES) is a malignant soft-tissue tumour which occurs particularly on the hand and forearm in young adults. The tumour grows slowly and metastasizes relatively late but has, nevertheless, a considerable mortality and morbidity because it is frequently erroneously diagnosed, both clinically and pathologically, either as a benign tumour or as a reactive inflammatory process. Two typical cases with diagnostic delays of 12 and 15 years, respectively, which required amputations through the upper arm or forearm are described. Even although ES is a rare tumour form, clinicians and pathologists should be aware of this possibility as, in the early stages, the tumour can frequently be treated effectively and radically by wide local excision without amputation.

摘要

上皮样肉瘤(ES)是一种恶性软组织肿瘤,尤其好发于年轻成年人的手部和前臂。该肿瘤生长缓慢,转移相对较晚,但由于在临床和病理上常被错误地诊断为良性肿瘤或反应性炎症过程,因此具有相当高的死亡率和发病率。本文描述了两例典型病例,诊断延误分别为12年和15年,均需要通过上臂或前臂进行截肢。尽管ES是一种罕见的肿瘤类型,但临床医生和病理学家应意识到这种可能性,因为在早期阶段,该肿瘤通常可通过广泛局部切除而非截肢进行有效且根治性的治疗。

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