Sihota Ramanjit, Kumar Sunil, Gupta Viney, Dada Tanuj, Kashyap Seema, Insan Rajpal, Srinivasan Geetha
Glaucoma Research Facility and Clinical Services, Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India.
Arch Ophthalmol. 2008 Jul;126(7):921-6. doi: 10.1001/archopht.126.7.921.
To prospectively analyze the clinical and ultrasonographic biomicroscopy (UBM) features in eyes with closed globe injury, at the initial examination, that would predict the occurrence of chronic traumatic glaucoma during a 6-month follow-up.
Forty consecutive eyes with closed globe injury and a chronically elevated intraocular pressure (IOP) of at least 21 mm Hg for a minimum of 3 months were diagnosed as having traumatic glaucoma and compared with 52 eyes with closed globe injury and no evidence of glaucoma.
The median grade of trabecular pigmentation on gonioscopy in eyes with traumatic glaucoma was 3 compared with 2 in eyes without glaucoma (P = .001). On UBM findings, 18 eyes with closed globe injury without glaucoma showed evidence of cyclodialysis, compared with 7 eyes with glaucoma (P = .001). The relative risk of developing traumatic glaucoma was also significantly higher with hyphema, elevated baseline IOP, angle recession of more than 180 degrees, lens displacement, and wider angles on UBM.
Clinically, the presence of increased pigmentation at the angle, elevated baseline IOP, hyphema, lens displacement, and angle recession of more than 180 degrees were significantly associated with the occurrence of chronic glaucoma after closed globe injury. On UBM findings, a wider angle and the absence of cyclodialysis were significant predictors for the subsequent development of traumatic glaucoma.
前瞻性分析闭合性眼球损伤患者初诊时的临床及超声生物显微镜(UBM)特征,以预测6个月随访期间慢性外伤性青光眼的发生。
连续40例闭合性眼球损伤且眼内压(IOP)持续至少3个月慢性升高至至少21 mmHg的患者被诊断为外伤性青光眼,并与52例闭合性眼球损伤且无青光眼证据的患者进行比较。
外伤性青光眼患者房角镜检查小梁色素沉着的中位分级为3级,无青光眼患者为2级(P = .001)。在UBM检查结果中,18例无青光眼的闭合性眼球损伤患者显示有睫状体脱离证据,而有青光眼的患者为7例(P = .001)。前房积血、基线IOP升高、房角后退超过180度、晶状体移位以及UBM检查显示房角较宽时,发生外伤性青光眼的相对风险也显著更高。
临床上,房角色素沉着增加、基线IOP升高、前房积血、晶状体移位以及房角后退超过180度与闭合性眼球损伤后慢性青光眼的发生显著相关。在UBM检查结果中,房角较宽且无睫状体脱离是外伤性青光眼后续发生的重要预测指标。