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主动脉-髂动脉重建术后脊髓或腰骶丛的缺血性损伤。

Ischemic injury to the spinal cord or lumbosacral plexus after aorto-iliac reconstruction.

作者信息

Gloviczki P, Cross S A, Stanson A W, Carmichael S W, Bower T C, Pairolero P C, Hallett J W, Toomey B J, Cherry K J

机构信息

Department of Neurology, Mayo Clinic, Rochester, Minnesota 55905.

出版信息

Am J Surg. 1991 Aug;162(2):131-6. doi: 10.1016/0002-9610(91)90174-c.

DOI:10.1016/0002-9610(91)90174-c
PMID:1862833
Abstract

Between January 1, 1980, and June 30, 1989, 9 patients (6 males and 3 females) developed ischemic injury to the spinal cord or lumbosacral plexus following 3,320 operations on the abdominal aorta (0.3%). The incidence of this complication was 0.1% (2 of 1,901) after elective and 1.4% (3 of 210) after emergency abdominal aortic aneurysm repair, and 0.3% (4 of 1,209) after repair for occlusive disease. Three of the latter had prior clinical evidence of distal embolization. Eight grafts were bifurcated (aorto-iliac:four, aorto-femoral: three, aorto-ilio-femoral:one). One patient underwent extra-anatomic revascularization. Only two patients had supraceliac aortic cross-clamping and one patient underwent exclusion of both internal iliac arteries. Four patients had hypotension. Early mortality was 22% (two of nine). Severe perioperative complications, mostly due to associated visceral and somatic ischemia and sepsis, were present in seven of the nine patients. The extent and type of the neurologic injury correlated with long-term outcome. Patients with ischemic injury of the lumbosacral roots or plexus had better recovery. Attention to the pelvic circulation and the collateral blood supply is important. Use of gentle technique to prevent embolization, avoidance of hypotension and prolonged supraceliac cross-clamping, revascularization of at least one internal iliac artery, and the use of heparin may decrease but not eliminate paraplegia. Once this unexpected complication occurs, careful neurologic evaluation should be done to localize the lesion and aid prognosis.

摘要

在1980年1月1日至1989年6月30日期间,9例患者(6例男性和3例女性)在3320例腹主动脉手术(发生率0.3%)后发生脊髓或腰骶丛缺血性损伤。该并发症的发生率在择期手术后为0.1%(1901例中有2例),在急诊腹主动脉瘤修复术后为1.4%(210例中有3例),在闭塞性疾病修复术后为0.3%(1209例中有4例)。后一组中有3例术前有远端栓塞的临床证据。8个移植物为分叉型(主动脉-髂动脉:4个,主动脉-股动脉:3个,主动脉-髂-股动脉:1个)。1例患者接受了解剖外血管重建术。仅2例患者进行了腹腔干上方主动脉交叉阻断,1例患者双侧髂内动脉被结扎阻断。4例患者出现低血压。早期死亡率为22%(9例中有2例)。9例患者中有7例出现严重的围手术期并发症,主要是由于相关的内脏和躯体缺血及脓毒症。神经损伤的程度和类型与长期预后相关。腰骶神经根或丛缺血性损伤的患者恢复较好。关注盆腔循环和侧支血供很重要。采用轻柔技术防止栓塞、避免低血压和长时间腹腔干上方交叉阻断、至少重建一条髂内动脉以及使用肝素可能会减少但不能消除截瘫。一旦发生这种意外并发症,应进行仔细的神经学评估以定位病变并辅助判断预后。

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