Chang Shih-Chieh, Liao Jiunn-Wang
Department of Veterinary Medicine, and Veterinary Medical Teaching Hospital, Graduate Institute of Veterinary Pathology, College of Veterinary Medicine, National Chung Hsing University, Taichung, Taiwan.
J Vet Med Sci. 2008 Jun;70(6):637-40. doi: 10.1292/jvms.70.637.
We report a liposarcoma at the mesojejunoileum that was widely excised, and then the intrahepatic metastatic liposarcoma was found. The dog was treated by two single-agent chemotherapy separately. The patient was an 8-year-old, male Dachshund, and was referred to our hospital owing to the significant distention of the left abdomen. Neither radiography nor ultrasonography detected the actual association of the tumor with the abdominal viscera before surgery. A large-sized tumor mass that adhered to the mesojejunoileum was explored by laparatomy. Final diagnosis of a pleomorphic liposarcoma was made by the routine histology and further identified by Oil Red O stain. The two single-agent chemotherapy including doxorubicin followed by capecitabine, however, failed to cause remission of the intrahepatic metastatic lesions. The patient died 22 months after operation and the cause of death was supposed to be metastatic liposarcoma.
我们报告了一例发生于空肠回肠系膜的脂肪肉瘤,该肿瘤被广泛切除,随后发现了肝内转移性脂肪肉瘤。这只狗先后接受了两种单药化疗。患者是一只8岁的雄性腊肠犬,因左腹明显肿胀被转诊至我院。术前,无论是X光检查还是超声检查均未发现肿瘤与腹部脏器的实际关联。通过剖腹探查发现一个附着于空肠回肠系膜的大型肿瘤块。通过常规组织学检查做出了多形性脂肪肉瘤的最终诊断,并通过油红O染色进一步确诊。然而,包括阿霉素后接卡培他滨的两种单药化疗均未能使肝内转移病灶缓解。患者术后22个月死亡,死因推测为转移性脂肪肉瘤。