伴有横纹肌溶解的致命性氨茶碱中毒。丹曲林治疗的潜在作用。

Fatal theophylline poisoning with rhabdomyolysis. A potential role for dantrolene treatment.

作者信息

Parr M J, Willatts S M

机构信息

Sir Humphry Davy Department of Anaesthesia, Bristol Royal Infirmary.

出版信息

Anaesthesia. 1991 Jul;46(7):557-9. doi: 10.1111/j.1365-2044.1991.tb09655.x.

DOI:10.1111/j.1365-2044.1991.tb09655.x

PMID:1862895

Abstract

A fatal case of theophylline poisoning is described. The patient developed rhabdomyolysis, renal failure and compartment syndrome, as well as the more usual features of severe theophylline poisoning. Dantrolene appeared to be useful in controlling the hypermetabolic state associated with the overdose and may have a role in future treatment.

摘要

本文描述了一例致命的茶碱中毒病例。该患者出现了横纹肌溶解、肾衰竭和骨筋膜室综合征，以及严重茶碱中毒的常见症状。丹曲林似乎有助于控制与过量用药相关的高代谢状态，可能在未来的治疗中发挥作用。