Clark Melody S
HGMP Resource Centre Genome Campus Hinxton, Cambridge CB2 4PP UK.
Comp Funct Genomics. 2003;4(2):182-93. doi: 10.1002/cfg.259.
Until recently, the Human Genome Project held centre stage in the press releases concerning sequencing programmes. However, in October 2001, it was announced that the Japanese puffer fish (Takifugu rubripes, Fugu) was the second vertebrate organism to be sequenced to draft quality. Briefly, the spotlight was on fish genomes. There are currently two other fish species undergoing intensive sequencing, the green spotted puffer fish (Tetraodon nigroviridis) and the zebrafish (Danio rerio). But this trio are, in many ways, atypical representations of the current state of fish genomic research. The aim of this brief review is to demonstrate the complexity of fish as a group of vertebrates and to publicize the 'lesser-known' species, all of which have something to offer.
直到最近,在有关测序项目的新闻发布中,人类基因组计划一直占据着核心位置。然而,2001年10月宣布,日本河豚(红鳍东方鲀,Fugu)是第二个完成高质量草图测序的脊椎动物。简而言之,焦点转向了鱼类基因组。目前还有另外两种鱼类正在进行密集测序,绿斑河豚(黑点多纪鲀)和斑马鱼(丹尼奥氏鱼)。但这三种鱼在许多方面都是鱼类基因组研究现状的非典型代表。这篇简短综述的目的是展示鱼类作为一组脊椎动物的复杂性,并宣传这些“不太知名”的物种,它们都有可提供的价值。