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[新生儿脓毒症中血液吸附诱导的免疫变化的纠正]

[Correction of the immunologic shifts induced by hemosorption in sepsis of the newborn].

作者信息

Murav'ev O V, Estrin V V, Vol'f V E, Sinichkin A A

出版信息

Anesteziol Reanimatol. 1991 Mar-Apr(2):59-61.

PMID:1862995
Abstract

Alongside with a positive clinical effect, hemosorption (HS) leads to the elimination of humoral immunity factors (Ig, FN) from the blood, having no effect on the phagocytic activity of leukocytes. Massive immunocorrection in doses 2-3 times higher than the age-matched ones, increases considerably the levels of IgG and FN. Immunomodulating effect of HS is enhanced when HS is combined with ultraviolet blood irradiation.

摘要

除了具有积极的临床效果外,血液吸附(HS)还能导致血液中体液免疫因子(Ig、FN)的清除,且对白细胞的吞噬活性没有影响。剂量比年龄匹配者高2 - 3倍的大规模免疫纠正,可显著提高IgG和FN的水平。当血液吸附与紫外线血液照射联合使用时,其免疫调节作用会增强。

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