Lazarev V V, Popova T G, Vodolazov Iu A
Anesteziol Reanimatol. 1991 Mar-Apr(2):63-6.
In 17 children aged 7 to 14 years angiography of the extremities (AGE) was performed under general anesthesia by intravenous calypsol injection without premedication with cholinolytics (group I, monoanesthesia) or with premedication with atropine and neuroleptics (diazepam, droperidol; group II). It has been established that calypsol, in both groups, had a short-term moderate stimulating effect on the cardiac function and an insignificant effect on the respiratory function, which was not essential for the assessment of hemodynamic parameters during AGE. Muscle relaxation was more marked in children of group II, mainly due to the use of neuroleptics. In children of group II muscle relaxation was insignificant, this was associated with certain difficulties during AG. A technique of calypsol anesthesia during AGE in children has been elaborated, it is recommended to use calypsol in combination with neuroleptics, and to strengthen anesthesia by additional calypsol administration prior to the injection of contrast agents.
对17名7至14岁儿童在全身麻醉下进行四肢血管造影（AGE），通过静脉注射卡立普索，I组未使用胆碱能阻滞剂进行术前用药（单纯麻醉），II组使用阿托品和抗精神病药（地西泮、氟哌利多）进行术前用药。结果表明，两组中的卡立普索对心脏功能有短期中度刺激作用，对呼吸功能影响不显著，这对AGE期间血流动力学参数的评估并非至关重要。II组儿童的肌肉松弛更为明显，主要是由于使用了抗精神病药。I组儿童的肌肉松弛不明显，这与AG期间的某些困难有关。已制定了儿童AGE期间卡立普索麻醉技术，建议将卡立普索与抗精神病药联合使用，并在注射造影剂前额外给予卡立普索以加强麻醉。
